Publications
In Press
Liu, J.,*^ Shi, Z.,* Fabbricatore, J. L., McMains, J. T., Worsdale, A., Jones, E. C., Wang, Y., & Sweet, L. H. (in press). Vaping and smoking cue reactivity in young adult non-smoking electronic cigarette users: a functional neuroimaging study. Nicotine and Tobacco Research. https://doi.org/10.1093/ntr/ntae257
2025
Shi, Z.,^ Langleben, D. D., Rott, D., Albanese, M., & Elman, I. (2025). Blood pressure response to extended-release naltrexone in heroin and prescription opioid users and its implications for cardiovascular morbidity. Journal of Addictive Diseases, 43(1), 77–78. https://doi.org/10.1080/10550887.2024.2327739
Pereira-Rufino, L. S., Gobbo, D. R., Conte, R., de Sino, R. M., de Oliveira, N. N., Fidalgo, T. M., Sato, J. R., Carrete, H., Jr., Souza-Formigoni, M. L. O., Shi, Z., Vissoci, J. R. N., Wiers, C. E., & Céspedes, I. C.^ (2025). Reduced gray matter volume in limbic and cortical areas is associated with anxiety and depression in alcohol use disorder patients. Psychiatry Research: Neuroimaging, 347, 111946. https://doi.org/https://doi.org/10.1016/j.pscychresns.2025.111946
2024
Shi, Z.,^ Li, X., Todaro, D. R., Cao, W., Lynch, K. G., Detre, J. A., Loughead, J., Langleben, D. D.,* & Wiers, C. E.* (2024). Medial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder – a longitudinal structural magnetic resonance imaging study. Translational Psychiatry, 14, 360. https://doi.org/10.1038/s41398-024-03061-0
Li, X., Kass, G., Wiers, C. E., & Shi, Z.^ (2024). The brain salience network at the intersection of pain and substance use disorders: insights from functional neuroimaging research. Current Addiction Reports, 11, 797–808. https://doi.org/10.1007/s40429-024-00593-9
Todaro, D. R., Volkow, N. D., Langleben, D. D., Shi, Z.,^ & Wiers, C. E.^ (2024). Collateral damage: neurological correlates of non-fatal overdose in the era of fentanyl-xylazine. Neuroscience Insights, 19, 26331055241247156. https://doi.org/10.1177/26331055241247156
Wang, X., Manza, P., Li, X., Ramos-Rolón, A., Hager, N., Wang, G. J., Volkow, N. D., Hu, Y., Shi, Z.,*^ & Wiers, C. E.*^ (2024). Reduced brain network segregation in alcohol use disorder: associations with neurocognition. Addiction Biology, 29(12), e13446. https://doi.org/10.1111/adb.13446
Li, X., Shi, Z., Todaro, D., Pond, T., Byanyima, J., Vesslee, S., Reddy, R., Nanga, R. P. R., Kass, G., Ramchandani, V., Kranzler, H. R., Vendruscolo, J. C. M., Vendruscolo, L. F., & Wiers, C. E.^ (2024). Ketone supplementation dampens subjective and objective responses to alcohol: evidence from a preclinical rat study and a randomized, cross-over trial in healthy volunteers. International Journal of Neuropsychopharmacology, 27(2), pyae009. https://doi.org/10.1093/ijnp/pyae009
Li, X.,* Ramos-Rolón, A. P.,* Kass, G., Pereira-Rufino, L. S., Shifman, N., Shi, Z., Volkow, N. D.,^ & Wiers, C. E.^ (2024). Imaging neuroinflammation in individuals with substance use disorders. Journal of Clinical Investigation, 134(11), e172884. https://doi.org/10.1172/JCI172884
2023
Li, X., Langleben, D. D., Lynch, K. G., Wang, G. J., Elman, I., Wiers, C. E.,*^ & Shi, Z.*^ (2023). Association between body mass index and treatment completion in extended-release naltrexone-treated patients with opioid dependence. Frontiers in Psychiatry, 14, 1247961. https://doi.org/10.3389/fpsyt.2023.1247961
Shi, Z., Wang, A. L., Fairchild, V. P., Aronowitz, C. A., Padley, J. H., Lynch, K. G., Loughead, J., & Langleben, D. D.^ (2023). Effects of emotional arousal on the neural impact and behavioral efficacy of cigarette graphic warning labels. Addiction, 118(5), 914–924. https://doi.org/10.1111/add.16112
Shi, Z.,*^ Wang, A. L.,* Fairchild, V. P., Aronowitz, C. A., Lynch, K. G., Loughead, J., & Langleben, D. D. (2023). Addicted to green: priming effect of menthol cigarette packaging on brain response to smoking cues. Tobacco Control, 32(e1), e45–e52. https://doi.org/10.1136/tobaccocontrol-2021-056639
Shi, Z., Li, X., Kampman, K. M., Childress, A. R., Wiers, C. E., & Langleben, D. D.^ (2023). Depressive symptomatology is associated with smaller reductions in drug cue reactivity during extended-release naltrexone treatment of opioid use disorder. Journal of Clinical Psychiatry, 84(3), 22br14567. https://doi.org/10.4088/JCP.22br14567
Shi, Z., Li, X., Byanyima, J. I., O’Brien, C. P., Childress, A. R., Lynch, K. G., Loughead, J., Wiers, C. E.,*^ & Langleben, D. D.*^ (2023). Effects of current smoking severity on brain gray matter volume in opioid use disorder - a voxel-based morphometry study. American Journal of Drug and Alcohol Abuse, 49(2), 180–189. https://doi.org/10.1080/00952990.2023.2169616
Todaro, D. R., Li, X., Pereira-Rufino, L. S., Manza, P., Nasrallah, I. M., Das, S., Childress, A. R., Kranzler, H. R., Volkow, N. D., Langleben, D. D., Shi, Z.,*^ & Wiers, C. E.*^ (2023). Hippocampal volume loss in individuals with a history of non-fatal opioid overdose. Addiction Biology, 28(10), e13336. https://doi.org/10.1111/adb.13336
Adams, A. R., Li, X., Byanyima, J. I., Vesslee, S. A., Nguyen, T. D., Wang, Y., Moon, B., Pond, T., Kranzler, H. R., Witschey, W. R., Shi, Z.,* & Wiers, C. E.*^ (2023). Peripheral and central iron measures in alcohol use disorder and aging: a quantitative susceptibility mapping pilot study. International Journal of Molecular Sciences, 24(5), 4461. https://doi.org/10.3390/ijms24054461
Byanyima, J. I.,* Li, X.,* Vesslee, S. A., Kranzler, H. R., Shi, Z.,^ & Wiers, C. E.^ (2023). Metabolic profiles associated with opioid use and opioid use disorder: a narrative review of the literature. Current Addiction Reports, 10(3), 581–593. https://doi.org/10.1007/s40429-023-00493-4
Liu, Y.,* Zhao, X.,* Hu, W., Ren, Y., Wei, Z., Ren, X., Tang, Z., Wang, N., Chen, H., Li, Y., Shi, Z., Qin, S., & Yang, J.^ (2023). Neural habituation during acute stress signals a blunted endocrine response and poor resilience. Psychological Medicine, 53(16), 7735–7745. https://doi.org/10.1017/S0033291723001666
2022
Li, X., Shi, Z., Byanyima, J., Morgan, P. T., van der Veen, J. W., Zhang, R., Deneke, E., Wang, G. J., Volkow, N. D., & Wiers, C. E.^ (2022). Brain glutamate and sleep efficiency associations following a ketogenic diet intervention in individuals with alcohol use disorder. Drug and Alcohol Dependence Reports, 5, 100092. https://doi.org/10.1016/j.dadr.2022.100092
2021
Shi, Z.,^ Langleben, D. D., O'Brien, C. P., Childress, A. R., & Wiers, C. E. (2021). Multivariate pattern analysis links drug use severity to distributed cortical hypoactivity during emotional inhibitory control in opioid use disorder. NeuroImage: Clinical, 32, 102806. https://doi.org/10.1016/j.nicl.2021.102806
Shi, Z., Jagannathan, K., Padley, J. H., Wang, A. L., Fairchild, V. P., O’Brien, C. P., Childress, A. R., & Langleben, D. D.^ (2021). The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder. Addiction Biology, 26(4), e12977. https://doi.org/10.1111/adb.12977
2020
Wang, A. L.,^ Shi, Z., Elman, I., & Langleben, D. D. (2020). Reduced cigarette smoking during injectable extended-release naltrexone treatment for opioid use disorder. American Journal of Drug and Alcohol Abuse, 46(4), 472–477. https://doi.org/10.1080/00952990.2020.1741001
Chen, Y., Shen, Y., Shi, Z., Zhang, X., Li, H., Xu, X., Guan, L., Han, S., & Yang, J.^ (2020). Mortality salience impairs self-referential processing: neurophysiological and behavioral evidence. Current Psychology, 39, 782–792. https://doi.org/10.1007/s12144-019-00193-1
2019
Shi, Z.,^ Jagannathan, K., Wang, A. L., Fairchild, V. P., Lynch, K. G., Suh, J. J., Childress, A. R., & Langleben, D. D. (2019). Behavioral and accumbal responses during an affective Go/No-go task predict adherence to injectable naltrexone treatment in opioid use disorder. International Journal of Neuropsychopharmacology, 22(3), 180–185. (Featured as Editor’s Choice) https://doi.org/10.1093/ijnp/pyz002
Shi, Z., Wang, A. L., Aronowitz, C. A., Cappella, J. N., Romer, D., & Langleben, D. D.^ (2019). Connectivity between visual and auditory cortices mediates the influence of argument strength on the effectiveness of smoking-cessation videos among smokers low in sensation seeking. Psychology Research and Behavior Management, 12, 531–542. https://doi.org/10.2147/prbm.s183394
Wang, A. L.,^ Shi, Z., Fairchild, V. P., Aronowitz, C. A., & Langleben, D. D. (2019). Emotional salience of the image component facilitates recall of the text of cigarette warning labels. European Journal of Public Health, 29(1), 153–158. https://doi.org/10.1093/eurpub/cky059
Peng, M.,^ Wu, S.,^ Shi, Z., Jiang, K., Shen, Y., Dedovic, K., & Yang, J.^ (2019). Brain regions in response to character feedback associated with the state self-esteem. Biological Psychology, 148, 107734. https://doi.org/10.1016/j.biopsycho.2019.107734
2018
Shi, Z., Wang, A. L., Jagannathan, K., Fairchild, V. P., O’Brien, C. P., Childress, A. R., & Langleben, D. D.^ (2018). Effects of extended-release naltrexone on the brain response to drug-related stimuli in patients with opioid use disorder. Journal of Psychiatry & Neuroscience, 43(4), 254–261. https://doi.org/10.1503/jpn.170036
Shi, Z., & Han, S.^ (2018). Distinct effects of reminding mortality and physical pain on the default-mode activity and activity underlying self-reflection. Social Neuroscience, 13(3), 372–383. https://doi.org/10.1080/17470919.2017.1329165
Qin, J.,^ Shi, Z., Ma, Y., & Han, S. (2018). Gender and neural substrates subserving implicit processing of death-related linguistic cues. Cognitive Processing, 19, 63–71. https://doi.org/10.1007/s10339-017-0847-0
Jiang, K., Wu, S., Shi, Z., Liu, M., Peng, M., Shen, Y., & Yang, J.^ (2018). Activations of the dorsolateral prefrontal cortex and thalamus during agentic self-evaluation are negatively associated with trait self-esteem. Brain Research, 1692, 134–141. https://doi.org/10.1016/j.brainres.2018.05.017
An, S.,^ Han, X., Wu, B., Shi, Z., Marks, M., Wang, S., Wu, X.,^ & Han, S.^ (2018). Neural activation in response to the two sides of emotion. Neuroscience Letters, 684, 140–144. https://doi.org/10.1016/j.neulet.2018.07.011
Wang, A. L.,^ Lowen, S. B., Elman, I., Shi, Z., Fairchild, V. P., Bouril, A., Gur, R. C., & Langleben, D. D. (2018). Sustained opioid antagonism modulates striatal sensitivity to baby schema in opioid use disorder. Journal of Substance Abuse Treatment, 85, 70–77. https://doi.org/10.1016/j.jsat.2017.10.007
2017
Shi, Z., Wang, A. L., Aronowitz, C. A., Romer, D., & Langleben, D. D.^ (2017). Individual differences in the processing of smoking-cessation video messages: an imaging genetics study. Biological Psychology, 128, 125–131. https://doi.org/10.1016/j.biopsycho.2017.07.019
Shi, Z.,^ Wang, A. L., Emery, L. F., Sheerin, K. M., & Romer, D. (2017). The importance of relevant emotional arousal in the efficacy of pictorial health warnings for cigarettes. Nicotine & Tobacco Research, 19(6), 750–755. https://doi.org/10.1093/ntr/ntw322
Han, X., He, K., Wu, B., Shi, Z., Liu, Y., Luo, S., Wei, K., Wu, X., & Han, S.^ (2017). Empathy for pain motivates actions without altruistic effects: evidence of motor dynamics and brain activity. Social Cognitive and Affective Neuroscience, 12(6), 893–901. https://doi.org/10.1093/scan/nsx016
2016
Shi, Z., Wang, A. L., & Langleben, D. D.^ (2016). Playing it safe: a video game probing the relationship between addiction, gender, and avoidance. Journal of Clinical Psychiatry, 77(3), 395–397. https://doi.org/10.4088/jcp.16com10752
Shi, Z., Ma, Y., Wu, B., Wu, X., Wang, Y., & Han, S.^ (2016). Neural correlates of reflection on actual versus ideal self-discrepancy. NeuroImage, 124(Pt A), 573–580. https://doi.org/10.1016/j.neuroimage.2015.08.077
Wang, A. L.,^ Lowen, S. B., Shi, Z., Bissey, B., Metzger, D. S., & Langleben, D. D. (2016). Targeting modulates audiences’ brain and behavioral responses to safe sex video ads. Social Cognitive and Affective Neuroscience, 11(10), 1650–1657. https://doi.org/10.1093/scan/nsw070
Yang, J.,^ Xu, X., Chen, Y., Shi, Z., & Han, S.^ (2016). Trait self-esteem and neural activities related to self-evaluation and social feedback. Scientific Reports, 6, 20274. https://doi.org/10.1038/srep20274
2015
Mahmoodi, A., Bang, D., Olsen, K., Zhao, Y. A., Shi, Z., Broberg, K., Safavi, S., Han, S., Nili Ahmadabadi, M., Frith, C. D., Roepstorff, A., Rees, G., & Bahrami, B.^ (2015). Equality bias impairs collective decision-making across cultures. Proceedings of the National Academy of Sciences of the United States of America, 112(12), 3835–3840. https://doi.org/10.1073/pnas.1421692112
Meyer, M. L.,^ Masten, C. L., Ma, Y., Wang, C., Shi, Z., Eisenberger, N. I., Lieberman, M. D., & Han, S.^ (2015). Differential neural activation to friends and strangers links interdependence to empathy. Culture and Brain, 3, 21–38. https://doi.org/10.1007/s40167-014-0023-7
Luo, S., Ma, Y., Liu, Y., Li, B., Wang, C., Shi, Z., Li, X., Zhang, W., Rao, Y., & Han, S.^ (2015). Interaction between oxytocin receptor polymorphism and interdependent culture values on human empathy. Social Cognitive and Affective Neuroscience, 10(9), 1273–1281. https://doi.org/10.1093/scan/nsv019
2014
Varnum, M. E. W.,*^ Shi, Z.,* Chen, A., Qiu, J., & Han, S.^ (2014). When “your” reward is the same as “my” reward: self-construal priming shifts neural responses to own vs. friends’ rewards. NeuroImage, 87, 164–169. https://doi.org/10.1016/j.neuroimage.2013.10.042
Luo, S., Shi, Z., Yang, X., Wang, X., & Han, S.^ (2014). Reminders of mortality decrease midcingulate activity in response to others’ suffering. Social Cognitive and Affective Neuroscience, 9(4), 477–486. https://doi.org/10.1093/scan/nst010
Ma, Y.,^ Li, B., Wang, C., Shi, Z., Sun, Y., Sheng, F., Zhang, Y., Zhang, W., Rao, Y., & Han, S. (2014). 5-HTTLPR polymorphism modulates neural mechanisms of negative self-reflection. Cerebral Cortex, 24(9), 2421–2429. https://doi.org/10.1093/cercor/bht099
2013
Shi, Z., & Han, S.^ (2013). Transient and sustained neural responses to death-related linguistic cues. Social Cognitive and Affective Neuroscience, 8(5), 573–578. https://doi.org/10.1093/scan/nss034
Liu, X.,* Shi, Z.,* Ma, Y., Qin, J., & Han, S.^ (2013). Dynamic neural processing of linguistic cues related to death. PLOS One, 8(6), e67905. https://doi.org/10.1371/journal.pone.0067905
Meyer, M. L., Masten, C. L., Ma, Y., Wang, C., Shi, Z., Eisenberger, N. I., & Han, S.^ (2013). Empathy for the social suffering of friends and strangers recruits distinct patterns of brain activation. Social Cognitive and Affective Neuroscience, 8(4), 446–454. https://doi.org/10.1093/scan/nss019
2012
de Greck, M.,^ Shi, Z., Wang, G., Zuo, X., Yang, X., Wang, X., Northoff, G., & Han, S.^ (2012). Culture modulates brain activity during empathy with anger. NeuroImage, 59(3), 2871–2882. https://doi.org/10.1016/j.neuroimage.2011.09.052
(*equal contribution; ^corresponding author)